Beckman Coulter

Beckman Coulter

Clinical Chemistry Analysers and Assays:

Clinical chemistry analysers and assays are used to measure specific chemicals and biomarkers in biological samples, helping diagnose diseases and monitor organ function. These systems can perform a wide range of routine and specialized tests.

DxC 500 AU Chemistry Analyzer

A powerful and reliable benchtop immunoassay analyzer featuring a space-saving design, user-friendly features and a complete menu of more than 50 tests

Main specifications:

Specification

Details

Analytical method

Fully automated, random-access clinical chemistry system with STAT capability

Analytical principles

Spectrophotometry and potentiometry

Assay types

Endpoint, rate, fixed point and indirect ISE

Analytical method

Colorimetry, turbidimetry, latex agglutination and indirect ISE

Chemistry menu capacity

>135 preprogrammed, photometrics currently available (including LIH + HbA1c (Thb, HbA1c + HbA1c%) and ISE)

Throughput

·       400 photometric tests per hour, up to 800 with ISEISE

·       maximum test per hour: 600 if ISE only

·       HbA1c maximum tests per hour: 65 if HbA1c only

Sample types (assay dependent)

Serum, Plasma, Urine, CSF, Whole blood

Sample management/capacity

·       168 sample tubes (24 racks of 7 tubes), unique continuous loading feature

·       Refrigerated STAT carousel: 22 samples can be run simultaneously (cal, QC and routine samples)

Sample container sizes

Primary and secondary tubes: diameter between 11.5 mm and 16 mm; height between 55 mm and 102 mm; nested micro cups and sample cups

Sample volume

1.0 μL–25 μL in 0.1 μL increments (assay dependent)

Sample Barcode symbology

NW7, EAN13, CODE 39, CODE 128, ISBT-128, 2 of 5 standard, 2 of 5 interleaved mixed readable (max. six types at the same time, except if using ISBT-128)

Compartment temperatures

·       STAT wheel: 39.2°F to 50°F (4.5°C to 12°C)

·       Reagent compartment: 39.2°F to 50°F (4.5°C to 12°C)

Reagent storage capacity

76 positions in a single reagent carousel (refrigerated between 39.2°F (4°C) and 53.6°F (12°C); bottle sizes: 15 mL, 30 mL, 60 mL)

Barcoded reagents

Automatic tracking of: Available tests, Expiration date, Lot number

Reagent volume

10 μL–250 μL (1 μL increments)

Total reaction volume

90 μL–350 μL

Reaction cuvette

Permanent glass cuvettes

Reaction time

Up to 8 minutes, 37.5 seconds

Reaction temperature

98.6°F ± 0.5°F (37°C ± 0.3°C)

Reaction incubation method

Dry bath

Photometric range

0 OD–3.0 OD

Wavelength

13 different wavelengths between 340 nm and 800 nm

Automated sample pre-dilution

Repeat run with increased or decreased sample volume or sample pre-dilution (1, 3, 5, 10, 15, 20, 25, 50, 75, up to 100 times)

Sample quality analysis

·       Lipemia, hemolysis and icterus indices

·       Clot detection and probe crash protection

Calibration

·       Calibration curve stability up to 90 days (assay dependent)

·       Calibrator value assignment by 2D barcode

·       Calibration curves and parameters displayed on screen

Quality control

·       Shewhart day-to-day management (Levey-Jennings method)

·       Multi-rule control (Westgard method)

Reflex testing

User-defined

Calculated result

·       Pre-defined for the commonly used calculations

·       User-defined



DxC 500i Clinical Analyser

Where Flexibility Drives Productivity

Meet your partner for integrated testing with a simplified workflow. The space-saving DxC 500i Clinical Analyser delivers high-quality chemistry and immunoassay results you can trust for your low-volume lab.

Specification

Details

Analytical method

Fully automated, random-access integrated system with clinical chemistry and immunoassay modules

Analytical principles

Spectrophotometry, potentiometry, and chemiluminescence

Assay types

·        Chemistry: Endpoint, rate, fixed point, indirect ISE

·        Immunoassay: Competitive assay, Sandwich assay, and Antibody detection assay

Analytical method

·        Chemistry: Colorimetry, turbidimetry, latex agglutination, and indirect ISE

·        Immunoassay: Paramagnetic coated antibody/antigen

Chemistry menu capacity

>170 preprogrammed assays currently available

Throughput

400 photometric tests per hour, up to 800 with ISE100 immunoassay tests per hour (one-step assays)

ISE maximum test per hour: 600 if ISE onlyHbA1c maximum tests per hour: 65 if HbA1c only

Sample types (assay dependent)

Serum, plasma, urine, CSF, whole blood, and amniotic fluid

Sample management/capacity

168 sample tubes (24 racks of 7 tubes), unique continuous loading feature

Independent analysis:

Chemistry: 22 samples in refrigerated STAT carousel

Immunoassay: 60 samples in 6 carousel racks

Barcoded reagents

Automatic tracking of: available tests, expiration date, lot number

Sample container sizes

Sample tubes:

·        13 × 75 mm, 13 × 100 mm, 16 × 100 mm

·        Sarstedt S-Monovette 4.9 mL, 5.5 mL, 7.5 mL

·         

Cups/insert cups:

·        0.5 mL, 2.5 mL, 3.0 mL cups1.0 mL, 2.0 mL insert cups, pediatric insert

·        Auto aliquot

Sample volume (assay dependent)

 

·        Chemistry: 1.0–25 μL in 0.1 μL increments (assay dependent)

·        Immunoassay: 10–110 μL

Sample barcode symbology

Codabar (NW-7), CODE 39, CODE 128, ISBT-128, Interleaved 2 of 5

Compartment temperatures

Chemistry:

·        Chemistry reagent compartment: 39.2°F to 53.6°F (4°C to 12°C)

·        STAT wheel: 39.2°F to 53.6°F (4°C to 12°C)

·        Cuvette wheel: 98.6°F ± 0.5°F (37°C ± 0.3°C)

 

Immunoassay:

·        Reagent compartment: 33°F to 41°F (1°C to 5°C)

·        Maintains air and reagent temperature at 37.4°F to 50°F (3°C to 10°C)

·        Incubator and wash/read wheel: 97.5°F ± 0.5°F (36.4°C ± 0.3°C)

Reagent storage capacity

·        Chemistry: 76 positions in a refrigerated reagent carousel that holds 15 mL, 30 mL, and 60 mL bottle sizes

·        Immunoassay: 24 positions in refrigerated reagent carousel

Reaction cuvette

·        Chemistry: Permanent glass cuvettes

·        Immunoassay: Disposable reaction vessels

Sample quality analysis

·        Lipemia, hemolysis, and icterus indices

·        Clot detection and probe crash protection

Calibration (assay dependent)

·        Chemistry: calibration curve stability up to 90 days

·        Immunoassay: calibration stability up to 63 days

·        Calibration curves and parameters displayed on screen

·        Calibrator setpoint entry through barcode scan

Quality control

Shewhart day-to-day management (Levey-Jennings method)

Multi-rule control (Westgard method)

Dimensions and weight

Analyzer with monitor:

·        Weight: Dry, 1,430 pounds (<650 kg)

·        Length: 100 in (254 cm)

·        Height: 48.8 in (124 cm)

·        Height with monitor: 63.0 in (160 cm)

·        Depth: 30.3 in (77 cm)

Clearance Requirements

Clearance around the analyzer for ventilation:

·        Rear: minimum of 24 in (64 cm)

·        Left: minimum of 20 in (50 cm)

·        Right: minimum of 20 in (50 cm)

·        Front: minimum of 25 in (63.5 cm)

·        Top (from the top of the chemistry analyzer): Minimum of 49 in (124 cm)

Waste requirements

Chemistry module drain location:

·        Maximum distance: 33 ft (10 m) from the system

·        Maximum height: 5 ft (1.5 m) from the floor

Chemistry module drain volume:

·        Concentrated waste: 5.5 L/hour (normal), 7.5 L/hour HbA1c

·        Diluted waste: 12 L/hour

Immunoassay module drain location:

·        Maximum distance 9.8 ft (3 m) from the system

·        Maximum height 3 ft (0.9 m) from the floor

 

Immunoassay module drain volume:1 L/hour

Immunoassay module solid waste (RVs):

RVs collected in RV waste bag (300 RV capacity)

Water supply requirements

Maximum water consumption: 20 L/hour

Water type: Deionized CAP type II or better, bacteria free

Continuous flow supply

Resistivity: > 0.5 MΩ∙cm filtered with a 0.5 μm filter

Power and environmental requirements

Power supply: 200V, 208V, 220V, 230V, 240V, 50/60Hz, 3.5kVA

Computer

·        Storage: 960GB SSD

·        Operating system: Windows 10

·        External communication types: RS232 serial interface

·        Ethernet: LAN using TCP/IP

Monitor

Touchscreen display: 21.5 in (54.6 cm) diagonal TFT LCD with projected capacitive touch

Pixels: 1920 × 1080 RGB

Operating environment

·        Ambient temperature: 64°F to 82°F (18°C to 28°C)

·        Humidity: 20% to 80% RH (without condensation)

·        Altitude: Maximum 2,000 m (6,561 ft) above sea level

·        Noise level: <75 dBA

Communication modes

Serial or TCP (1 or 2 physical) connection to LIS per ASTM protocol

DxC 700 AU Chemistry Analyzer

Get the right results at the right time with one system. The DxC 700 AU clinical chemistry analyzer is the latest innovation in a line of reliable chemistry systems for the mid- to high-volume laboratory. The DxC 700 AU combines the best-loved (and time-tested) features of the popular DxC and AU series of clinical chemistry analyzers. This powerful combination delivers maximal uptime, high reliability, and precise performance.

Specification

Details

Photometric Throughput with ISE (tests/hour)

800/1,200 with ISE

Number of Onboard Assays with ISE

63

Sample Volume (µL)

1.0–25.0

Sample Load Capacity (Routine/STAT)

150 (15 racks × 10 samples),22 samples by carousel

Clot Detection and Auto-clearing (Mechanism)

Yes

Open Channel Capability

Yes

Software

Windows 1.0

AU5800 Series Clinical Chemistry Analysers

Give your high- and ultra high-volume core laboratory a performance boost. Clinical chemistry analyzers in the AU5800 series are the fastest in the industry, processing up to 2,000 tests per hour with a full menu of assays, including Therapeutic Drug Monitoring (TDM) and Drugs of Abuse. Increase lab productivity with continuous operation, powerful throughput and scalable capacity up to four modules.   

AU480 Chemistry Analyzer

Compact, reliable and cost-effective

Put the power of versatility to work for your lab with a smart and efficient clinical chemistry analyzer solution. The AU480 chemistry analyzer is the ideal primary clinical chemistry analyzer for low- to mid-volume hospitals and laboratories, or dedicated specialty chemistry or STAT analyzer for larger laboratories. With throughput of up to 400 photometric tests per hour (up to 800 with ISEs), increased onboard testing, reduced sample volume and easy operation, the AU480 delivers efficiency for laboratories around the world. 

Specification

Details

Analytical System

Fully automated, random access chemistry system with STAT capability

Analytical Principle

Spectrophotometry and potentiometry

Analytical Types

Endpoint, rate, fixed point and indirect ISE

Analytical Methods

Colorimetry, turbidimetry, latex agglutination, homogeneous EIA, indirect ISE

Simultaneously Processed Analytes

60 photometric tests + 3 ISE, 120 pre-programmed onboard tests

Throughput

400 photometric tests/hour; maximum of 800 with ISE

ISE Throughput

200 samples/hr. Maximum tests/hr: 600 if ISE only

Sample Types

Serum, plasma, urine, other

Sample Feeder

Racks with 10 samples each (barcodes on primary tubes and on racks); capacity of 80 samples; continuous loading

Sample Tubes

Primary and secondary tubes; diameter from 11.5 to 16 mm; height from 55 to 102 mm, nestled micro sample cups

STAT samples

Up to 22 positions for STAT samples via cooled turntable. Easy-to-operate interrupts between tests. Auto-repeat run capability.

Sample Volume

1–25 μl in 0.1 μl steps (1–25 μl for repeats)

Reagent Capacity

76 positions for (R1+R2, detergent position). Holds 15, 30 and 60 ml bottles.

Reagent Storage

Refrigerated (4–12°C)

Reagent Volume

R1: 10–250 μl; R2: 10–250 μl (in 1 μl increment)

Total Reaction Volume

90–350 μl

Reaction Cuvette

Permanent glass cuvettes

Reaction Time

Up to 8 minutes, 37.5 seconds

Reaction Incubation

37°C, dry bath

Photometry System

Direct assay through the reaction cuvette (0–3.0 OD) mono and bichromatic measurements possible

Wavelength

13 different wavelengths between 340–800 nm

Calibration

Auto calibration, cooled calibrator positions; master calibration established by two-dimensional barcode

Quality Control

Auto QC, cooled QC positions

Rerun

1. Auto rerun and manual rerun available2. Automatic sample increase, decrease or normal repeat3. Reflex testing

Sample Pre-dilution

Dilution ratio: Fixed to 3, 5, 10, 15, 20, 25, 50, 76 or 100

Test Requisition

Individual and profile test requisition via online, mouse, function keys and touch-screen

Sample Integrity

Lipaemia, Haemolysis and Icterus analysis. Sample clot detection and probe crash protection.

Online

RS232C. Full uni- and bidirectional communication possible.

Software

Windows 7®

Data Storage

Sample number: 100,000 samples.

Reaction Data: 200,000 tests.

Dimensions (W × H × D)

ANL: 1450 mm × 1205 mm × 770 mm

Power Supply

100–240 V; 60 Hz / < 3.5 kVA

 

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