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illumina

illumina Genomics Solutions:

Sequencing and microarray products by illumina for diverse applications.

illumina is the global leader in the manufacturing of Next Generation Sequencing systems used by life sciences and researchers to isolate and analyze genes. illumina’s proprietary microarray (Bead Array) technology uses microscopic silica beads that can carry samples through the genotyping process. The tests allow medical researchers to determine what genetic combinations are associated with various diseases, enabling faster diagnosis, better drug targets, and individualized treatment.

Next Generation Sequencers – NGS

Micro Array Systems

iSeq 100 Sequencing System

Affordable and Accessible Benchtop Sequencer

Measuring one cubic foot in size, the iSeq 100 delivers NGS discovery power in the most compact format of any illumina sequencer to date. The iSeq 100 represents another step toward establishing NGS as a standard for discovery research and routine genomic testing for a wide range of customers, markets and applications.The iSeq 100 Sequencing System makes next-generation sequencing easier and more affordable than ever. Designed for simplicity, it allows labs of all sizes to sequence DNA and RNA at the push of a button.

Popular Applications & Methods:

  • Small Whole-Genome Sequencing (microbe, virus)
  • Targeted Gene Sequencing (amplicon-based, gene panel)
  • Targeted Gene Expression Profiling
  • miRNA & Small RNA Analysis
  1. Run Time: 9.5–19 hrs
  2. Maximum Output: 1.2 Gb
  3. Maximum Reads Per Run: 4M 
  4. Maximum Read Length: 2 × 150 bp

MiniSeq

An Affordable Bench-top Sequencer

 

The MiniSeq System delivers the power and confidence of proven illumina next-generation sequencing (NGS) technology in an accessible sequencing solution. It features cost-efficient sequencing, even for low numbers of samples. Its streamlined workflow enables rapid sequencing of both DNA and RNA. The small footprint allows it to fit seamlessly into laboratories, with no need for specialized, ancillary equipment.

Popular Applications & Methods:

 

  • Small Whole-Genome Sequencing (microbe, virus)
  • Targeted Gene Sequencing (amplicon-based, gene panel)
  • Targeted Gene Expression Profiling
  • miRNA & Small RNA Analysis
  • 16S Metagenomic Sequencing
  1. RunTime: 4–24 hours 
  2. Maximum_Output: 7.5 Gb
  3. Maximum Reads Per Run: 25M
  4. Maximum Read Length: 2 × 150 bp

MiSeq

Focused power on the MiSeq System

 

Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths.

Popular Applications & Methods:

 

  • Small Whole-Genome Sequencing (microbe, virus)
  • Targeted Gene Sequencing (amplicon-based, gene panel)
  • Targeted Gene Expression Profiling
  • miRNA & Small RNA Analysis
  • DNA-Protein Interaction Analysis (ChIP-Seq)
  • 16S Metagenomic Sequencing
  1. Run Time: 4–55 hours 
  2. Maximum Output: 15 Gb
  3.  Maximum Reads Per Run: 25M 
  4. Maximum Read Length: 2 × 300 bp

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NovaSeq 6000

Scalable throughput for studies of all sizes

 

NovaSeq 6000 Sequencing System is by far our most powerful instrument, designed to adapt to your needs so groundbreaking discoveries are always within reach. It’s flexible, scalable science on your terms.

Popular Applications & Methods:

 

  • Large Whole-Genome Sequencing (human, plant, animal)
  • Small Whole-Genome Sequencing (microbe, virus)
  • Exome & Large Panel Sequencing (enrichment-based)
  • Targeted Gene Sequencing (amplicon-based, gene panel)
  • Single-Cell Profiling (scRNA-Seq, scDNA-Seq, oligo tagging assays)
  • Transcriptome Sequencing (total RNA-Seq, mRNA-Seq, gene expression profiling)
  • Chromatin Analysis (ATAC-Seq, ChIP-Seq)
  • Methylation Sequencing
  • Metagenomic Profiling (shotgun metagenomics, metatranscriptomics)
  • Cell-Free Sequencing & Liquid Biopsy Analysis
  1. Run Time: ~13 – 38 hours (dual SP flow cells)
    ~13–25 hours (dual S1 flow cells)
    ~16–36 hours (dual S2 flow cells)
    ~44 hours (dual S4 flow cells)
  2. Maximum Output: 6000 Gb 
  3. Maximum Reads Per Run: 20 billion 
  4. Maximum Read Length: 2 x 250

NextSeq 550

Fuel your lab with NextSeq 550

 

Flexible benchtop sequencing for a variety of research applications

Popular Applications & Methods:

 

  • Small Whole-Genome Sequencing (microbe, virus)
  • Exome & Large Panel Sequencing (enrichment-based)
  • Targeted Gene Sequencing (amplicon-based, gene panel)
  • Single-Cell Profiling (scRNA-Seq, scDNA-Seq, oligo tagging assays)
  • Transcriptome Sequencing (total RNA-Seq, mRNA-Seq, gene expression profiling)
  • Targeted Gene Expression Profiling
  • miRNA & Small RNA Analysis
  • DNA-Protein Interaction Analysis (ChIP-Seq)
  • Methylation Sequencing
  • 16S Metagenomic Sequencing
  • Metagenomic Profiling (shotgun metagenomics, metatranscriptomics)
  • Cell-Free Sequencing & Liquid Biopsy Analysis
  1. Run Time: 12–30 hours
  2. Maximum Output: 120 Gb 
  3. Maximum Reads Per Run: 400 million
  4. Maximum Read Length: 2 × 150 bp

NextSeq 1000 & 2000

Easier than ever. Accelerated decision making.

 

Experience our simplest workflow yet with dry instrumentation, easier run set up and DRAGEN on-board for 6x faster secondary analysis.

Popular Applications & Methods:

 

  • Small Whole-Genome Sequencing (microbe, virus)
  • Exome & Large Panel Sequencing (enrichment-based)
  • Targeted Gene Sequencing (amplicon-based, gene panel)
  • Single-Cell Profiling (scRNA-Seq, scDNA-Seq, oligo tagging assays)
  • Transcriptome Sequencing (total RNA-Seq, mRNA-Seq, gene expression profiling)
  • Targeted Gene Expression Profiling
  • miRNA & Small RNA Analysis
  • DNA-Protein Interaction Analysis (ChIP-Seq)
  • Methylation Sequencing
  • 16S Metagenomic Sequencing
  • Metagenomic Profiling (shotgun metagenomics, metatranscriptomics)
  • Cell-Free Sequencing & Liquid Biopsy Analysis
  1. Run Time: 11-48 hours 
  2. Maximum Output: 330 Gb
  3. Maximum Reads Per Run: 1.1 billion
  4. Maximum Read Length: 2 × 150 bp

Micro Array Systems (iScan System)

Array scanner for extensive applications

 

The iScan System can scan thousands of array samples per day, without sacrificing data quality or reproducibility. It supports our expansive portfolio of genetic analysis assays, from high-throughput genotyping to DNA methylation analysis.

Popular Applications & Methods:

  • Genotyping Arrays
  • Methylation Array Analysis
  • Cytogenomics
  1. Array Scan Time: 0.3 min. to 26 min. per sample 
  2. Sequencer Run Time: N/A 
  3. Automation Capability: Automatable with liquid handling robots and array loaders.

NextSeq 550 System

Flexible next-generation sequencing (NGS) and cytogenomic microarray scanning all on one instrument

 

The NextSeq 550 System combines tried-and-true instrument technologies and tunable output with sequencing and array capabilities. Users can run transcriptome, targeted resequencing, genotyping, and other applications all on one platform.

Popular Applications & Methods:

  • Methylation Array Analysis
  • Cytogenomics
    Exome Sequencing
    Targeted Gene Sequencing (amplicon, gene panel)
  • Whole-Transcriptome Sequencing
  • Gene Expression Profiling with mRNA-Seq
  • miRNA & Small RNA Analysis
  • DNA-Protein Interaction Analysis
  • Methylation Sequencing
    Metagenomics
  1. Array Scan Time: 3.3 min. to 5 min. per sample 
  2. Sequencer Run Time: ~11 to 29 hours 
  3. Automation Capability: N/A
  • Coding Transcriptome Analysis
  • Cytogenomics
  • DNA-Protein Interaction Analysis
  • Gene Expression Analysis
  • Genomic Surveillance
  • Genotyping
  • Inherited Disease Variant Analysis
  • Metagenomics
  • miRNA and Small RNA Analysis
  • Population Studies
  • Rare and Undiagnosed Disease Variant Analysis
  • Targeted Analysis
  • Tumor Immunogenicity Analysis
  • Whole-Genome Analysis
  • Whole-Transcriptome Analysis

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